Acetic Acid → N-Cyclopropyl-N-cyclopropylmethyl-N-[7-(2-methoxy-4,6-dimethylphenyl)-2-(methylsulfanyl)pyrazolo[1,5-a]pyridin-3-yl]amine

HRID 152995

Reaction equation

HRID 152995 reaction equation
[C:27]([BH3-:28])#[N:29].[CH2:36]([O:37][C:39]1([O:38][Si:42]([CH3:43])([CH3:44])[CH3:45])[CH2:40][CH2:41]1)[CH3:46].[CH3:47][OH:48].[CH3:49][C:50](=[O:51])[OH:52].[CH:1]1([CH2:4][NH:5][c:6]2[c:7]([S:25][CH3:26])[n:8][n:9]3[c:10]2[cH:11][cH:12][cH:13][c:14]3-[c:15]2[c:16]([O:23][CH3:24])[cH:17][c:18]([CH3:22])[cH:19][c:20]2[CH3:21])[CH2:2][CH2:3]1.[Na+:30].[Na+:31].[OH:32][C:33](=[O:34])[O-:35]>>[CH:1]1([CH2:4][N:5]([c:6]2[c:7]([S:25][CH3:26])[n:8][n:9]3[c:10]2[cH:11][cH:12][cH:13][c:14]3-[c:15]2[c:16]([O:23][CH3:24])[cH:17][c:18]([CH3:22])[cH:19][c:20]2[CH3:21])[CH:39]2[CH2:40][CH2:41]2)[CH2:2][CH2:3]1

Participants

8

Reactant 7

HCID 176Acetic AcidHCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ion2×HCID 498716Cyano-borohydrideHCID 2734686(1-Ethoxycyclopropoxy)trimethylsilaneHCID 21984576N-cyclopropylmethyl-N-[7-(2-methoxy-4,6-dimethylphenyl)-2-(methylsulfanyl)pyrazolo[1,5-a]pyridin-3-yl]amine

Product 1

HCID 21984645N-Cyclopropyl-N-cyclopropylmethyl-N-[7-(2-methoxy-4,6-dimethylphenyl)-2-(methylsulfanyl)pyrazolo[1,5-a]pyridin-3-yl]amine

Sources & evidence

ORD record
ord-f9a7d36a718e4bb4bbafa6bc2ed4ff94
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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