5-Bromosalicylaldehyde → HCID 178449915, compound

HRID 1531248

Reaction equation

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:10])=[C:6]([CH:9]=1)[CH:7]=O.[C:11]([NH:15][OH:16])([CH3:14])([CH3:13])[CH3:12]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([OH:10])=[C:6]([CH:7]=[N+:15]([C:11]([CH3:14])([CH3:13])[CH3:12])[O-:16])[CH:9]=1

Participants

Reactant 2

HCID 728635-Bromosalicylaldehyde

HCID 98586N-tert-butylhydroxylamine

Product 1

HCID 178449915HCID 178449915, compound

Procedure

The title compound was prepared according to the procedure described in Example 1 using 5-bromo-2-hydroxybenzaldehyde and N-tert-butylhydroxylamine. The title compound was isolated in 68.7% yield as a yellow crystalline solid, m.p. 118.7° C. (Rf=0.65 on a silica gel plate using 1:1 EtOAc/hexanes as an eluant).

Workup

customThe title compound was prepared

Sources & evidence

ORD record: ord-de7a2748ebe648fd8b933d3c61c58394
Source dataset: uspto-grants-2001_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06197826B1

Linked notes

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