Zinc → 5-Amino-1-(4-bromo-2-fluoro-phenyl)-6,7-difluoro-4-methoxy-1,3-dihydro-benzoimidazol-2-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:25])[c:5](-[n:8]2[c:9](=[O:24])[nH:10][c:11]3[c:12]2[c:13]([F:23])[c:14]([F:22])[c:15]([N+:19]([O-:20])=[O:21])[c:16]3[O:17][CH3:18])[cH:6][cH:7]1.[NH2:26][c:27]1[c:28]([F:29])[c:30]([F:31])[c:32]2[n:33](-[c:34]3[cH:35][cH:36][c:37]([I:38])[cH:39][c:40]3[F:41])[c:42](=[O:43])[nH:44][c:45]2[c:46]1[O:47][CH3:48].[Zn:49]>>[Br:1][c:2]1[cH:3][c:4]([F:25])[c:5](-[n:8]2[c:9](=[O:24])[nH:10][c:11]3[c:12]2[c:13]([F:23])[c:14]([F:22])[c:15]([NH2:19])[c:16]3[O:17][CH3:18])[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-104d57183b2c4b6fbdb13b72fa03edbf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)