N-{3-[1-(3-amino propyl)4-piperidinyl]phenyl}acetamide → N-(3-{4-[3-(Acetylamino)phenyl]-1-piperidinyl}propyl)-4-(2,4-difluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxamide
Reaction equation
[F:21][c:22]1[c:23]([CH:29]2[C:30]([C:37](=[O:38])[OH:39])=[C:31]([CH3:36])[NH:32][C:33](=[O:35])[CH2:34]2)[cH:24][cH:25][c:26]([F:28])[cH:27]1.[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][CH:8]([c:11]2[cH:12][c:13]([NH:17][C:18]([CH3:19])=[O:20])[cH:14][cH:15][cH:16]2)[CH2:9][CH2:10]1>>[NH:1]([CH2:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][CH:8]([c:11]2[cH:12][c:13]([NH:17][C:18]([CH3:19])=[O:20])[cH:14][cH:15][cH:16]2)[CH2:9][CH2:10]1)[C:37]([C:30]1=[C:31]([CH3:36])[NH:32][C:33](=[O:35])[CH2:34][CH:29]1[c:23]1[c:22]([F:21])[cH:27][c:26]([F:28])[cH:25][cH:24]1)=[O:38]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-a95fe966687d4648bae782991fa69de5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)