2-(Bromomethyl)-5-(trifluoromethyl)furan → 7'-chloro-1'-((5-(trifluoromethyl)furan-2-yl)methyl)-5,6-dihydro-2H-spiro[benzofuro[6,5-b]furan-3,3'-indolin]-2'-one
Reaction equation
[Br:44][CH2:45][c:46]1[o:47][c:48]([C:51]([F:52])([F:53])[F:54])[cH:49][cH:50]1.[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[NH:8][C:9](=[O:22])[C:10]21[c:11]2[c:12]([cH:15][c:16]3[c:20]([cH:21]2)[CH2:19][CH2:18][O:17]3)[O:13][CH2:14]1.[Cl:55][CH2:56][c:57]1[cH:58][n:59][c:60]([O:61][CH3:62])[n:63][cH:64]1.[NH:23]1[c:24]2[c:25]([cH:26][cH:27][cH:28][cH:29]2)[C:30]2([CH2:31][O:32][c:33]3[cH:34][c:35]4[c:36]([cH:37][c:38]32)[CH2:39][CH2:40][O:41]4)[C:42]1=[O:43]>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[N:8]([CH2:45][c:46]1[o:47][c:48]([C:51]([F:52])([F:53])[F:54])[cH:49][cH:50]1)[C:9](=[O:22])[C:10]21[c:11]2[c:12]([cH:15][c:16]3[c:20]([cH:21]2)[CH2:19][CH2:18][O:17]3)[O:13][CH2:14]1
