2-Chloropyridine-4-boronic acid → [1-(2-Chloro-pyridin-4-yl)-5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-(4-cyclopropanesulfonyl-piperazin-1-yl)-methanone

HRID 1543425

Reaction equation

HRID 1543425 reaction equation
[CH:1]1([S:4](=[O:5])(=[O:6])[N:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:14])[c:15]3[nH:16][c:17]4[cH:18][cH:19][c:20]([C:24](=[O:25])[N:26]5[CH2:27][CH2:28][N:29]([CH:32]([CH3:33])[CH3:34])[CH2:30][CH2:31]5)[cH:21][c:22]4[cH:23]3)[CH2:11][CH2:12]2)[CH2:2][CH2:3]1.[Cl:35][c:36]1[n:37][cH:38][cH:39][c:40]([B:42]([OH:43])[OH:44])[cH:41]1>>[CH:1]1([S:4](=[O:5])(=[O:6])[N:7]2[CH2:8][CH2:9][N:10]([C:13](=[O:14])[c:15]3[n:16](-[c:40]4[cH:39][cH:38][n:37][c:36]([Cl:35])[cH:41]4)[c:17]4[cH:18][cH:19][c:20]([C:24](=[O:25])[N:26]5[CH2:27][CH2:28][N:29]([CH:32]([CH3:33])[CH3:34])[CH2:30][CH2:31]5)[cH:21][c:22]4[cH:23]3)[CH2:11][CH2:12]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 51515952-Chloropyridine-4-boronic acidHCID 68535679(4-Cyclopropanesulfonyl-piperazin-1-yl)-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone

Product 1

HCID 86621935[1-(2-Chloro-pyridin-4-yl)-5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-(4-cyclopropanesulfonyl-piperazin-1-yl)-methanone

Sources & evidence

ORD record
ord-bb32d701212c40d59509e218cab49c6c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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