1,4-Dioxane → 1,1-Dimethylethyl 4-[4-{2-fluoro-3-[(3-furanylsulfonyl)amino]phenyl}-5-(2-methyl-4-pyrimidinyl)-1,3-thiazol-2-yl]-4-methyl-1-piperidinecarboxylate
Reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][O:50][CH2:51]1.[CH3:43][Zn:44][CH3:45].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:27]3[c:28]([F:42])[c:29]([NH:33][S:34](=[O:35])(=[O:36])[c:37]4[cH:38][o:39][cH:40][cH:41]4)[cH:30][cH:31][cH:32]3)[n:10][c:11]([C:13]3([CH3:26])[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[s:12]2)[n:7]1>>[c:2]1([CH3:43])[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:27]3[c:28]([F:42])[c:29]([NH:33][S:34](=[O:35])(=[O:36])[c:37]4[cH:38][o:39][cH:40][cH:41]4)[cH:30][cH:31][cH:32]3)[n:10][c:11]([C:13]3([CH3:26])[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[s:12]2)[n:7]1Participants
4
