5-Ethynylpyrimidin-2-amine → 5-[8-Trifluoromethyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-b]pyridazin-3-ylethynyl]-pyrimidin-2-ylamine
Reaction equation
[C:25](#[CH:26])[c:27]1[cH:28][n:29][c:30]([NH2:33])[n:31][cH:32]1.[I:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[n:7][c:8](-[c:15]1[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]1)[cH:9][c:10]2[C:11]([F:12])([F:13])[F:14]>>[c:2]1([C:26]#[C:25][c:27]2[cH:28][n:29][c:30]([NH2:33])[n:31][cH:32]2)[cH:3][n:4][c:5]2[n:6]1[n:7][c:8](-[c:15]1[cH:16][cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]1)[cH:9][c:10]2[C:11]([F:12])([F:13])[F:14]Participants
3
Sources & evidence
- ORD record
- ord-6cc8f2a84bfb4d45a42d3b82891edbf7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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