Acetone → 3-(3-amino-4-chloro-6-fluoro-2-methoxyphenyl)-1-methyl-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione

HRID 1554082

Reaction equation

HRID 1554082 reaction equation
[C:24](=[O:25])([O-:26])[O-:27].[CH3:30][I:31].[CH3:32][C:33](=[O:34])[CH3:35].[K+:28].[K+:29].[NH2:1][c:2]1[c:3]([O:22][CH3:23])[c:4](-[n:10]2[c:11](=[O:21])[nH:12][c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][c:15]2=[O:16])[c:5]([F:9])[cH:6][c:7]1[Cl:8]>>[NH2:1][c:2]1[c:3]([O:22][CH3:23])[c:4](-[n:10]2[c:11](=[O:21])[n:12]([CH3:24])[c:13]([C:17]([F:18])([F:19])[F:20])[cH:14][c:15]2=[O:16])[c:5]([F:9])[cH:6][c:7]1[Cl:8]

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 6328Methyl iodideHCID 19660Carbonate IonHCID 183150803-(3-amino4-chloro-6-fluoro-2-methoxyphenyl)-6-trifluoromethyl-2,4-(1H,3H)-pyrimidinedione

Product 1

HCID 183150613-(3-amino-4-chloro-6-fluoro-2-methoxyphenyl)-1-methyl-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione

Sources & evidence

ORD record
ord-4b9b0228265946fea5035259c71d0d77
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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