Toluene → 1-(Piperidin-4-yl)-6-methoxyindoline

Reaction equation

[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[N:15]1[CH2:16][CH2:17][CH:18]([N:21]2[CH2:22][CH2:23][c:24]3[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][c:29]32)[CH2:19][CH2:20]1.[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[Cl:1][C:2]([O:3][CH:4]([Cl:5])[CH3:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][CH:18]([N:21]2[CH2:22][CH2:23][c:24]3[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][c:29]32)[CH2:19][CH2:20]1

Participants

Reactant 3

HCID 1140Toluene

HCID 5213051-Chloroethyl chloroformate

HCID 220380801-(1-Benzylpiperidin-4-yl)-6-methoxy-2,3-dihydroindole

Product 1

HCID 220381801-(Piperidin-4-yl)-6-methoxyindoline

Sources & evidence

ORD record: ord-2fa5afa466fd4847971cdff1f57909f5
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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