Acetate → N-{2-[1-(4-difluoromethoxy-3-ethoxy-phenyl)-2-methanesulfonyl-ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}-acetamide

HRID 155773

Reaction equation

HRID 155773 reaction equation
[C:21]([CH3:22])(=[O:23])[NH:24][c:25]1[c:26]2[c:27]([cH:33][cH:34][cH:35]1)[C:28](=[O:29])[O:30][C:31]2=[O:32].[CH3:37][C:38](=[O:39])[O-:40].[CH3:41][C:42](=[O:43])[OH:44].[F:1][CH:2]([O:3][c:4]1[c:5]([O:17][CH2:18][CH3:19])[cH:6][c:7]([CH:10]([CH2:11][S:12](=[O:13])(=[O:14])[CH3:15])[NH2:16])[cH:8][cH:9]1)[F:20].[Na+:36]>>[F:1][CH:2]([O:3][c:4]1[c:5]([O:17][CH2:18][CH3:19])[cH:6][c:7]([CH:10]([CH2:11][S:12](=[O:13])(=[O:14])[CH3:15])[N:16]2[C:28](=[O:29])[c:27]3[c:26]([c:25]([NH:24][C:21]([CH3:22])=[O:23])[cH:35][cH:34][cH:33]3)[C:31]2=[O:30])[cH:8][cH:9]1)[F:20]

Participants

6

Reactant 5

HCID 175AcetateHCID 176Acetic AcidHCID 923Sodium ionHCID 2261213-Acetamidophthalic AnhydrideHCID 58800079HCID 58800079, compound

Product 1

HCID 10368552N-{2-[1-(4-difluoromethoxy-3-ethoxy-phenyl)-2-methanesulfonyl-ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}-acetamide

Sources & evidence

ORD record
ord-9571cd614dc34b3e8924c8b6c0e32635
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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