2,6-Dihydroxy-4-methylquinoline → 4-Methyl-6-{3-[4-(4-fluorobenzyl)-piperazin-1-yl]-propoxy}-2-oxo-1,2-dihydroquinoline
Reaction equation
[CH3:1][c:2]1[cH:3][c:4](=[O:13])[nH:5][c:6]2[cH:7][cH:8][c:9]([OH:12])[cH:10][c:11]12.[F:14][c:15]1[cH:16][cH:17][c:18]([CH2:19][N:20]2[CH2:21][CH2:22][N:23]([CH2:26][CH2:27][CH2:28][Cl:29])[CH2:24][CH2:25]2)[cH:30][cH:31]1>>[CH3:1][c:2]1[cH:3][c:4](=[O:13])[nH:5][c:6]2[cH:7][cH:8][c:9]([O:12][CH2:28][CH2:27][CH2:26][N:23]3[CH2:22][CH2:21][N:20]([CH2:19][c:18]4[cH:17][cH:16][c:15]([F:14])[cH:31][cH:30]4)[CH2:25][CH2:24]3)[cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-3bb8f69e16aa461ea9251a979a339036
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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