4-Methyl-1,3-oxazolidin-2-one → 3-[4-[4-(3-Cyclopropyl-5-methyl-2-pyridinyl)piperazine-1-carbonyl]-3-fluorophenyl]-4-methyl-1,3-oxazolidin-2-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:26])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH3:25])[cH:20][c:21]3[CH:22]3[CH2:23][CH2:24]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1.[CH3:27][CH:28]1[NH:29][C:30](=[O:33])[O:31][CH2:32]1>>[c:2]1([N:29]2[CH:28]([CH3:27])[CH2:32][O:31][C:30]2=[O:33])[cH:3][c:4]([F:26])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH3:25])[cH:20][c:21]3[CH:22]3[CH2:23][CH2:24]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-9770a715678c49188ccb986826495af4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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