Dichloromethane → 1-{6-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-2-pyrrolidin-1-ylmethyl-3,4-dihydro-2H-quinolin-1-yl}-ethanone
Reaction equation
[CH3:1][C:2]([O:3][C:5]([CH3:6])=[O:7])=[O:4].[Cl:39][CH2:40][Cl:41].[Cl:8][c:9]1[cH:10][cH:11][c:12](-[c:15]2[cH:16][cH:17][c:18]([C:21]#[C:22][c:23]3[cH:24][c:25]4[c:30]([cH:31][cH:32]3)[NH:29][CH:28]([CH2:33][N:34]3[CH2:35][CH2:36][CH2:37][CH2:38]3)[CH2:27][CH2:26]4)[n:19][cH:20]2)[cH:13][cH:14]1>>[C:5]([CH3:6])(=[O:7])[N:29]1[CH:28]([CH2:33][N:34]2[CH2:35][CH2:36][CH2:37][CH2:38]2)[CH2:27][CH2:26][c:25]2[cH:24][c:23]([C:22]#[C:21][c:18]3[cH:17][cH:16][c:15](-[c:12]4[cH:11][cH:10][c:9]([Cl:8])[cH:14][cH:13]4)[cH:20][n:19]3)[cH:32][cH:31][c:30]21Participants
4
Sources & evidence
- ORD record
- ord-0e257c3410614819be9375134d0f82f7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)