Pyridine → 5-Acetyloxy-7-methyl-3-(3-trifluoromethylphenyl)-5,6,7,8-tetrahydrocinnoline

HRID 1563429

Reaction equation

HRID 1563429 reaction equation
[CH3:1][CH:2]1[CH2:3][CH:4]([OH:22])[c:5]2[cH:6][c:7](-[c:12]3[cH:13][c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][cH:16][cH:17]3)[n:8][n:9][c:10]2[CH2:11]1.[CH3:23][C:24](=[O:25])[O:26][C:27](=[O:28])[CH3:29].[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[CH3:1][CH:2]1[CH2:3][CH:4]([O:22][C:24]([CH3:23])=[O:25])[c:5]2[cH:6][c:7](-[c:12]3[cH:13][c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][cH:16][cH:17]3)[n:8][n:9][c:10]2[CH2:11]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 7918Acetic AnhydrideHCID 99725287-Methyl-3-(3-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydrocinnolin-5-ol

Product 1

HCID 230867325-Acetyloxy-7-methyl-3-(3-trifluoromethylphenyl)-5,6,7,8-tetrahydrocinnoline

Sources & evidence

ORD record
ord-c15f1fce90e045b9a50a456425ac8abf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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