Acetic Acid → 2-Bromo-5-(4-chloro-phenyl)-pyridin-3-ylamine

Reaction equation

[Br:1][c:2]1[n:3][cH:4][c:5](-[c:11]2[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]2)[cH:6][c:7]1[N+:8]([O-:9])=[O:10].[C:21](=[O:22])([OH:23])[O-:24].[CH3:26][C:27](=[O:28])[OH:29].[Na+:25].[Sn:18]([Cl:19])[Cl:20]>>[Br:1][c:2]1[n:3][cH:4][c:5](-[c:11]2[cH:12][cH:13][c:14]([Cl:17])[cH:15][cH:16]2)[cH:6][c:7]1[NH2:8]

Participants

Reactant 5

HCID 176Acetic Acid

HCID 769Bicarbonate Ion

HCID 923Sodium Ion

HCID 24479Stannous Chloride

HCID 859696992-Bromo-5-(4-chlorophenyl)-3-nitropyridine

Product 1

HCID 859697042-Bromo-5-(4-chloro-phenyl)-pyridin-3-ylamine

Sources & evidence

ORD record: ord-c8886ebe310e48c2968e8818df7ccf18
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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