tert-butyl 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate → tert-butyl 4-(5-chloro-4-fluoro-2-hydroxyphenyl)-1H-pyrazole-1-carboxylate

Reaction equation

[CH3:11][C:12]1([CH3:13])[C:14]([CH3:15])([CH3:16])[O:17][B:18]([c:19]2[cH:20][n:21][n:22]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[cH:23]2)[O:31]1.[Cl:1][c:2]1[cH:3][c:4]([I:10])[c:5]([OH:9])[cH:6][c:7]1[F:8]>>[Cl:1][c:2]1[cH:3][c:4](-[c:19]2[cH:20][n:21][n:22]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[cH:23]2)[c:5]([OH:9])[cH:6][c:7]1[F:8]

Participants

Reactant 2

HCID 16217654tert-butyl 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate

HCID 594365134-Chloro-5-fluoro-2-iodophenol

Product 1

HCID 59436628tert-butyl 4-(5-chloro-4-fluoro-2-hydroxyphenyl)-1H-pyrazole-1-carboxylate

Sources & evidence

ORD record: ord-f2dfd327e9ec4ab8b3c12924ec219567
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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