Ammonia → 2-Chloro-5-(trifluoromethyl)-4-pyridinamine

Reaction equation

[CH3:13][OH:14].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([I:8])[cH:7]1.[NH3:15]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([NH2:15])[cH:7]1

Participants

Reactant 3

HCID 222Ammonia

HCID 887Methanol

HCID 27737912-Chloro-4-iodo-5-(trifluoromethyl)pyridine

Product 1

HCID 713061562-Chloro-5-(trifluoromethyl)-4-pyridinamine

Sources & evidence

ORD record: ord-1b8c67ce3d7e48bf9248b38705199e07
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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