Dichloromethane → 3-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-8-methyl-2-o-tolylisoquinolin-1(2H)-one

Reaction equation

[B:39]([Br:40])([Br:41])[Br:42].[Cl:43][CH2:44][Cl:45].[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH2:19][c:20]1[n:21](-[c:32]3[c:33]([CH3:38])[cH:34][cH:35][cH:36][cH:37]3)[c:22](=[O:31])[c:23]3[c:24]([CH3:30])[cH:25][cH:26][cH:27][c:28]3[cH:29]1)[n:9][c:10]2-[c:11]1[cH:12][c:13]([O:17][CH3:18])[cH:14][cH:15][cH:16]1>>[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH2:19][c:20]1[n:21](-[c:32]3[c:33]([CH3:38])[cH:34][cH:35][cH:36][cH:37]3)[c:22](=[O:31])[c:23]3[c:24]([CH3:30])[cH:25][cH:26][cH:27][c:28]3[cH:29]1)[n:9][c:10]2-[c:11]1[cH:12][c:13]([OH:17])[cH:14][cH:15][cH:16]1