2-Aminocyclohexanol → 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (2-hydroxy-cyclohexyl)-amide

HRID 157170

Reaction equation

HRID 157170 reaction equation
[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[NH2:21][CH:22]1[CH:23]([OH:28])[CH2:24][CH2:25][CH2:26][CH2:27]1>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:21][CH:22]3[CH:23]([OH:28])[CH2:24][CH2:25][CH2:26][CH2:27]3)[n:11]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 232862-AminocyclohexanolHCID 710872926-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid

Product 1

HCID 711056166-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (2-hydroxy-cyclohexyl)-amide

Sources & evidence

ORD record
ord-21ceb371a4a2453285ef82674d9df1b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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