tert-butyl N-(2-amino-4-(trifluoromethyl)phenyl)carbamate → (2-{3-Oxo-3-[3-(2-pyrrolidin-1-yl-pyridin-4-yl)-phenyl]-propionylamino}-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:18])[cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]1)=[O:19].[C:20]([CH3:22])([CH3:23])([O:24][C:25](=[O:21])[CH2:26][C:27]([c:28]1[cH:29][c:30](-[c:34]2[cH:35][c:36]([N:40]3[CH2:41][CH2:42][CH2:43][CH2:44]3)[n:37][cH:38][cH:39]2)[cH:31][cH:32][cH:33]1)=[O:45])[CH3:46]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:18][C:25](=[O:24])[CH2:26][C:27]([c:28]2[cH:29][c:30](-[c:34]3[cH:35][c:36]([N:40]4[CH2:41][CH2:42][CH2:43][CH2:44]4)[n:37][cH:38][cH:39]3)[cH:31][cH:32][cH:33]2)=[O:45])[cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]1)=[O:19]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-cdf7c5288d9449469f00926ff5881f46
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)