4-(Trifluoromethyl)thiazole-2-carboxylic acid → N-(6-acetyl-3-methoxy-2-methylphenyl)-4-(trifluoromethyl)-1,3-thiazole-2-carboxamide

Reaction equation

[C:26]([c:27]1[cH:28][cH:29][c:30]([O:31][CH3:32])[cH:33][c:34]1[NH:35][C:36]([c:37]1[s:38][cH:39][c:40]([CH:41]([CH3:42])[CH3:43])[n:44]1)=[O:45])(=[O:46])[CH3:47].[F:1][C:2]([c:3]1[n:4][c:5]([C:8](=[O:9])[OH:10])[s:6][cH:7]1)([F:11])[F:12].[NH2:13][c:14]1[c:15]([C:23]([CH3:24])=[O:25])[cH:16][cH:17][c:18]([O:21][CH3:22])[c:19]1[CH3:20]>>[F:1][C:2]([c:3]1[n:4][c:5]([C:8](=[O:10])[NH:13][c:14]2[c:15]([C:23]([CH3:24])=[O:25])[cH:16][cH:17][c:18]([O:21][CH3:22])[c:19]2[CH3:20])[s:6][cH:7]1)([F:11])[F:12]