3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride → 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylate

HRID 1573619

Reaction equation

HRID 1573619 reaction equation
[Cl:24][c:25]1[c:26](-[c:32]2[n:33][o:34][c:35]([CH3:40])[c:36]2[C:37](=[O:38])[Cl:39])[c:27]([Cl:31])[cH:28][cH:29][cH:30]1.[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[CH2:7][CH2:8][CH:9]([c:12]2[cH:13][c:14]([NH:18][C:19]([CH:20]([CH3:21])[CH3:22])=[O:23])[cH:15][cH:16][cH:17]2)[CH2:10][CH2:11]1>>[O:1]([CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[CH2:7][CH2:8][CH:9]([c:12]2[cH:13][c:14]([NH:18][C:19]([CH:20]([CH3:21])[CH3:22])=[O:23])[cH:15][cH:16][cH:17]2)[CH2:10][CH2:11]1)[C:37]([c:36]1[c:32](-[c:26]2[c:25]([Cl:24])[cH:30][cH:29][cH:28][c:27]2[Cl:31])[n:33][o:34][c:35]1[CH3:40])=[O:38]

Participants

3

Reactant 2

HCID 782123-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chlorideHCID 22048659N-(3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamide

Product 1

HCID 220494624-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylate

Sources & evidence

ORD record
ord-23ae11973e1046aba70a45a59838c56b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Linked notes

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