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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 157404Generated: October 26, 2026

Ethylbenzene → 8-(Tetrahydropyran-4-yl)-1,4-dioxa-spiro[4.5]decane-8-carbonitrile

https://huagongshe.com/reaction/157404

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylbenzeneHCID 7500—
ReactantTetrahydrofuranHCID 8028—
ReactantHeptaneHCID 8900—
ReactantLithium ionHCID 28486—
Reactant4-iodotetrahydro-2H-pyranHCID 2795506—
ReactantDiisopropylamideHCID 5062348—
Reactant1,4-Dioxaspiro[4.5]decane-8-carbonitrileHCID 11116433—
Product8-(Tetrahydropyran-4-yl)-1,4-dioxa-spiro[4.5]decane-8-carbonitrileHCID 67072827—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-feb6a5901dba46639d654ccbbe22c821
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)