1-Benzothiophene-3-sulfonyl chloride → [4-Amino-2-[1-(benzo[b]thiophene-3-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone

HRID 1575814Notes

Reaction equation

HRID 1575814 reaction equation
[NH2:1][c:2]1[n:3][c:4]([NH:19][CH:20]2[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:17][CH3:18])[cH:12][cH:13][c:14]([F:16])[cH:15]1.[s:26]1[c:27]2[c:28]([c:29]([S:31](=[O:32])(=[O:33])[Cl:34])[cH:30]1)[cH:35][cH:36][cH:37][cH:38]2>>[NH2:1][c:2]1[n:3][c:4]([NH:19][CH:20]2[CH2:21][CH2:22][N:23]([S:31]([c:29]3[c:28]4[c:27]([s:26][cH:30]3)[cH:38][cH:37][cH:36][cH:35]4)(=[O:32])=[O:33])[CH2:24][CH2:25]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:17][CH3:18])[cH:12][cH:13][c:14]([F:16])[cH:15]1

Participants

3

Reactant 2

HCID 27763401-Benzothiophene-3-sulfonyl chlorideHCID 9997668[4-Amino-2-(piperidin-4-ylamino)-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone

Product 1

HCID 21070416[4-Amino-2-[1-(benzo[b]thiophene-3-sulfonyl)-piperidin-4-ylamino]-pyrimidin-5-yl]-(5-fluoro-2-methoxy-phenyl)-methanone

Sources & evidence

ORD record
ord-11bbd00d22e84e69acb19f95a56f95b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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