HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitroamino-2-imidazoline → alpha-(2-Imidazolin-2-ylaminomethyl)-m-methylbenzyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitroamino-2-imidazoline | HCID 410042 | — |
| Reactant | 2-Amino-1-(3-methylphenyl)ethan-1-ol | HCID 13482511 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | alpha-(2-Imidazolin-2-ylaminomethyl)-m-methylbenzyl alcohol | HCID 53888914 | — |
Reaction Steps
A mixture of 8.2 parts of α-(aminomethyl)-m-methylbenzyl alcohol, 6,1 parts of 2-(nitramino)-2-imidazoline and 40 parts of xylene is stirred in an oil-bath at 150°-160°C, while almost all xylene is distilled off. The residue is diluted with a few parts of acetone and allowed to crystallize. The product is filtered off and recrystallized from 4-methyl-2-pentanone, yielding α-(2-imidazolin-2-ylaminomethyl)-m-methylbenzyl alcohol; m.p. 121°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03983133 |
| Source dataset | uspto-grants-1976_09 |
| ORD ID | ord-522e6db6ff9344f395e2cbef978ae442 |
| Source note | uspto-grants-1976_09 |