4-(4-Methoxyphenyl)but-3-en-2-one → HCID 12374368, compound

HRID 1577040

Reaction equation

HRID 1577040 reaction equation
[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH3:6][C:7]1[C:15]([CH3:17])([CH3:16])[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH+:8]=1.[CH3:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([CH:26]=[CH:27][C:28](=O)[CH3:29])=[CH:22][CH:21]=1>CO>[Cl:1]([O-:5])(=[O:4])(=[O:3])=[O:2].[CH3:29][C:28]1[N+:8]2[C:9]3[C:14]([C:15]([CH3:17])([CH3:16])[C:7]=2[CH:6]=[C:26]([C:23]2[CH:22]=[CH:21][C:20]([O:19][CH3:18])=[CH:25][CH:24]=2)[CH:27]=1)=[CH:13][CH:12]=[CH:11][CH:10]=3

Participants

4

Reactant 2

HCID 954144-(4-Methoxyphenyl)but-3-en-2-oneHCID 149131883H-Indole, 2,3,3-trimethyl-, perchlorate

Product 1

HCID 12374368HCID 12374368, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2,3,3-Trimethyl-3H-indolium perchlorate (5 g.) and 4-p-methoxyphenylbut-3-ene-2-one (10 g.) were heated together on the steam bath for three hours. The cooled mixture was diluted with methanol and filtered. The product was purified by recrystallization from acetonitrile. Yield 4.1 g.; m.p. 298°-300° .

Workup

  1. filtrationfiltered
  2. customThe product was purified by recrystallization from acetonitrile

Sources & evidence

ORD record
ord-10a387c8143d4b76b6e143ffaefdfae1
Source dataset
uspto-grants-1976_09
Patent number
US03983288

Linked notes

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