3'-Bromoacetophenone → 3-(3-Acetylphenyl)-1,3-oxazolidin-2-one

HRID 15776

Reaction equation

Br[C:2]1[CH:3]=[C:4]([C:8](=[O:10])[CH3:9])[CH:5]=[CH:6][CH:7]=1.[O:11]1[CH2:15][CH2:14][NH:13][C:12]1=[O:16]>>[C:8]([C:4]1[CH:3]=[C:2]([N:13]2[CH2:14][CH2:15][O:11][C:12]2=[O:16])[CH:7]=[CH:6][CH:5]=1)(=[O:10])[CH3:9]

Participants

Reactant 2

HCID 165023'-Bromoacetophenone

HCID 739492-Oxazolidinone

Product 1

HCID 457925063-(3-Acetylphenyl)-1,3-oxazolidin-2-one

Procedure

The title compound was prepared in quantitative yield according to the general procedure for the preparation of the amides, ureas and carbamates (Method A) starting from 1-(3-bromophenyl)ethanone and 1,3-oxazolidin-2-one.

Sources & evidence

ORD record: ord-f4c8956df284469bb0dbee4f7ef7bfdd
Source dataset: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07732600B2

Linked notes

Loading…