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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15788Generated: October 27, 2026

Isovaleryl chloride → 3-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)butanamide

https://huagongshe.com/reaction/15788

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsovaleryl chlorideHCID 66054—
Reactant3-(2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}anilineHCID 49852105—
Product3-Methyl-N-(3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)butanamideHCID 5747828564%

Reaction Steps

The title compound was prepared in 64% yield according to the general procedure for the preparation of the amides (Method B) starting from 3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}aniline (D6) and 3-methylbutanoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732600B2
Source datasetuspto-grants-2010_06
ORD IDord-0e33d2caa0f64ae2993a3ff2caa18759
Source noteuspto-grants-2010_06