Benzyl Alcohol → HCID 178476834, compound

HRID 1583732

Reaction equation

HRID 1583732 reaction equation
[OH:1][CH:2]([PH:4](=[O:6])[OH:5])[CH3:3].[CH2:7](O)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.O>C1C=CC=CC=1>[OH:1][CH:2]([PH:4](=[O:5])[O:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH3:3]

Participants

5

Reactant 3

HCID 244Benzyl AlcoholHCID 962WaterHCID 178476830HCID 178476830, compound

Product 1

HCID 178476834HCID 178476834, compoundYield 91.2%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A solution of α-hydroxyethylphosphinic acid (5.5 g) and benzyl alcohol (2.26 g) in benzene (50 ml) was heated for 8 hours with removal of water through a Dean-Stark apparatus. After cooling, the reaction mixture was washed with water, dried over magnesium sulfate and concentrated in vacuo to give 3.65 g (91.2%) of benzyl α-hydroxyethylphosphinate (Compound No. 36).

Workup

  1. temperatureAfter cooling
  2. washthe reaction mixture was washed with water
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-16302dc960c74e4580f5028245e59782
Source dataset
uspto-grants-1985_11
Patent number
US04554111

Linked notes

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