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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15867Generated: October 27, 2026

Acetamide → N-(4-Fluoro-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamide

https://huagongshe.com/reaction/15867

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetamideHCID 178—
Reactant5-{4-[2-(5-Bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinolineHCID 57444350—
ProductN-(4-Fluoro-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)acetamideHCID 5744434966%

Reaction Steps

The title compound was prepared in 66% yield according to the general procedure for the preparation of the amides, ureas and carbamates (Method A) starting from 5-{4-[2-(5-bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline and acetamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732600B2
Source datasetuspto-grants-2010_06
ORD IDord-800a26bd045545dd92f90a7e97ea1aed
Source noteuspto-grants-2010_06