Methyl isothiocyanate → HCID 18952274, compound
Reaction equation
[CH3:1][C:2]1[C:7]([NH2:8])=[C:6]([N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)[CH:5]=[CH:4][CH:3]=1.[CH3:15][N:16]=[C:17]=[S:18]>ClCCl>[CH3:15][NH:16][C:17]([NH:8][C:7]1[C:2]([CH3:1])=[CH:3][CH:4]=[CH:5][C:6]=1[N:9]1[CH2:14][CH2:13][O:12][CH2:11][CH2:10]1)=[S:18]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Reaction of 6-methyl-2-morpholinoaniline (8.75 g) with methyl isothiocyanate (4.7 g) in dichloromethane (50 ml ) at room temperature for four days yielded N-methyl-N-'-(6-methyl-2-morpholinophenyl)thiourea (m.p. 182°-183° C.).
Sources & evidence
- ORD record
- ord-84d45c2ea91e42578bcacb44c7ab0457
- Source dataset
- uspto-grants-1993_06
- Patent number
- US05223498
Reaction notes
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