Veratrylamine → N-(3-Bromo-5-methoxyphenyl)-2-[[(3,4-dimethoxyphenyl)methyl]amino]acetamide
Reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([NH:10][C:11](=[O:14])[CH2:12]Cl)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1.[CH3:15][O:16][C:17]1[CH:18]=[C:19]([CH2:25][NH2:26])[CH:20]=[CH:21][C:22]=1[O:23][CH3:24]>>[Br:1][C:2]1[CH:3]=[C:4]([NH:10][C:11](=[O:14])[CH2:12][NH:26][CH2:25][C:19]2[CH:20]=[CH:21][C:22]([O:23][CH3:24])=[C:17]([O:16][CH3:15])[CH:18]=2)[CH:5]=[C:6]([O:8][CH3:9])[CH:7]=1Participants
3
Procedure
In a manner similar to Preparation 12, react N-(3-bromo-5-methoxyphenyl)-2-chloroacetamide with 3,4-dimethoxybenzenemethanamine to obtain the title compound.
Workup
- customIn a manner similar to Preparation 12
Sources & evidence
- ORD record
- ord-12283023ab084aa9bf5142c259a5d459
- Source dataset
- uspto-grants-1993_06