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Glycine → Glyphosate

HRID 1589109
Notes
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Reaction equation

HRID 1589109 reaction equation
[NH2:1][CH2:2][C:3]([OH:5])=[O:4].[CH:6]([P:8](=[O:11])([OH:10])[OH:9])=O>>[CH2:2]([NH:1][CH2:6][P:8]([OH:11])([OH:10])=[O:9])[C:3]([OH:5])=[O:4]
ParticipantsProcedureSources & evidenceReaction notes

Participants

3

Reactant 2

HCID 750GlycineHCID 10154022Formylphosphonic Acid

Product 1

HCID 3496GlyphosateYield 27%

Procedure

Reaction of glycine and formylphosphonic acid was carried out under the conditions described in Example 6 except that the initial pH was 4.0. A 27% yield of glyphosate was obtained.

Sources & evidence

ORD record
ord-60a7585f28b24c6d804f1b52bf745df1
Source dataset
uspto-grants-1986_02
DOI
10.6084/m9.figshare.5104873.v1
Patent number
US04568432

Reaction notes

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On this pageParticipantsProcedureSources & evidenceReaction notes