Diethyl Ether → HCID 13178507, compound

Reaction equation

[C:1]([C:4]1[CH:9]=[C:8]([Br:10])[C:7]([OH:11])=[C:6]([Br:12])[CH:5]=1)(=[NH:3])[NH2:2].[CH2:13](Cl)[C:14]1[CH:22]=[CH:21][C:20]2[O:19][CH2:18][O:17][C:16]=2[CH:15]=1.C([O:26]CC)C>N1C=CC=CC=1>[CH2:18]1[O:19][C:20]2[CH:21]=[CH:22][C:14]([C:13]([O:11][C:7]3[C:6]([Br:12])=[CH:5][C:4]([C:1](=[NH:2])[NH2:3])=[CH:9][C:8]=3[Br:10])=[O:26])=[CH:15][C:16]=2[O:17]1

Participants

Procedure

To a solution of 5 g of 4-amidino-2,6-dibromophenol in 100 ml of pyridine, while being cooled in ice and stirred, was added 2.4 g of piperonyl chloride. The mixture was stirred for 30 minutes while being cooled in ice, then for 3 hours at room temperature, and mixed with about 300 cc of ethyl ether. The precipitate which was formed was collected by filtration and recrystallized from ethanol to obtain 4.8 g of colorless crystals of 4-amidino-2,6-dibromophenyl 3,4-methylenedioxybenzoate methanesulfonate.