HCID 53851186, compound → HCID 54249876, compound
Reaction equation
[CH3:1][C:2]1([CH3:26])[CH2:6][CH2:5][C:4]([CH3:8])([CH3:7])[CH:3]1[NH:9][C:10](=[O:25])[C:11]([NH:14]C(OCC1C=CC=CC=1)=O)([CH3:13])[CH3:12]>CO.[Pd]>[CH3:1][C:2]1([CH3:26])[CH2:6][CH2:5][C:4]([CH3:7])([CH3:8])[CH:3]1[NH:9][C:10](=[O:25])[C:11]([NH2:14])([CH3:13])[CH3:12]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
N-Cbz-2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl amide is dissolved in CH3OH and is hydrogenated over 5% Pd/C in a Parr hydrogenation apparatus. When the reaction is complete the mixture is filtered through Celite and concentrated to yield 2-aminoisobutyric acid 2,2,5,5-tetramethylcyclopentyl amide.
Workup
- filtrationis filtered through Celite
- concentrationconcentrated
Sources & evidence
- ORD record
- ord-3c7a49e6203c4a91bdc677129a819462
- Source dataset
- uspto-grants-1986_02
- Patent number
- US04572799
Reaction notes
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