3-(5-bromo-2-hydroxyphenyl)-3-(hydroxymethyl)-1,3-dihydro-2H-indol-2-one → 5-bromospiro[1-benzofuran-3,3'-indol]-2'(1'H)-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([OH:20])[c:6]([C:8]2([CH2:18][OH:19])[C:9](=[O:17])[NH:10][c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]32)[cH:7]1.[CH:21]1([CH2:22][CH2:23][N:24]2[c:25]3[c:26]([cH:27][cH:28][cH:29][cH:30]3)[C:31]([c:32]3[c:33]([OH:34])[cH:35][c:36]4[c:40]([cH:41]3)[O:39][CH2:38][O:37]4)([CH2:42][OH:43])[C:44]2=[O:45])[CH2:46][CH2:47]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:7]1)[C:8]1([C:9](=[O:17])[NH:10][c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]31)[CH2:18][O:19]2Participants
3
Sources & evidence
- ORD record
- ord-7e8f0a2afe0e45ad81f986d030d55147
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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