Dichloromethane → Methyl 5-fluoro-4-hydroxy-2-methoxybenzoate

Reaction equation

[Cl:31][CH2:32][Cl:33].[F:14][C:15]([F:16])([F:17])[S:18]([O-:19])(=[O:20])=[O:21].[F:22][n+:23]1[cH:24][c:25]([Cl:26])[cH:27][c:28]([Cl:29])[cH:30]1.[OH:1][c:2]1[cH:3][c:4]([O:12][CH3:13])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1>>[OH:1][c:2]1[cH:3][c:4]([O:12][CH3:13])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][c:11]1[F:14]

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 27245793,5-Dichloro-1-fluoropyridin-1-ium

HCID 2758875Trifluoromethanesulfonate

HCID 12532676Methyl 4-hydroxy-2-methoxybenzoate

Product 1

HCID 18914108Methyl 5-fluoro-4-hydroxy-2-methoxybenzoate

Sources & evidence

ORD record: ord-ec7eeff981714cffb612815a7782af67
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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