3-(Trifluoromethyl)cyclohexanone → (1RS,2RS,5RS)-3-(2-dimethylaminomethyl-1-hydroxy-5-trifluoromethyl-cyclohexyl)-phenol hydrochloride
Reaction equation
[CH3:1][N:2]([CH2:4][CH:5]1[CH2:10][CH2:9][CH:8]([C:11]([F:14])([F:13])[F:12])[CH2:7][C:6]1=[O:15])[CH3:3].FC(F)(F)[CH:18]1[CH2:23][CH2:22][CH2:21][C:20](=[O:24])[CH2:19]1.CN(C(Cl)[Cl:31])C>C(#N)C>[ClH:31].[CH3:3][N:2]([CH2:4][CH:5]1[CH2:10][CH2:9][CH:8]([C:11]([F:14])([F:12])[F:13])[CH2:7][C:6]1([C:18]1[CH:19]=[C:20]([OH:24])[CH:21]=[CH:22][CH:23]=1)[OH:15])[CH3:1]Participants
5
