Pyridine → 1-methyl-1H-pyrazole-3-sulfonic acid benzyl-(1-oxo-1,2,3,4-tetrahydro-isoquinolin-6-yl)-amide

HRID 159617

Reaction equation

HRID 159617 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][c:9]1[cH:10][c:11]2[c:16]([cH:17][cH:18]1)[C:15](=[O:19])[NH:14][CH2:13][CH2:12]2.[CH3:26][n:27]1[n:28][c:29]([S:32](=[O:33])(=[O:34])[Cl:35])[cH:30][cH:31]1.[CH3:36][C:37]#[N:38].[cH:20]1[cH:21][cH:22][n:23][cH:24][cH:25]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([c:9]1[cH:10][c:11]2[c:16]([cH:17][cH:18]1)[C:15](=[O:19])[NH:14][CH2:13][CH2:12]2)[S:32]([c:29]1[n:28][n:27]([CH3:26])[cH:31][cH:30]1)(=[O:33])=[O:34]

Participants

5

Reactant 4

HCID 1049PyridineHCID 6342AcetonitrileHCID 134744661-Methyl-1H-pyrazole-3-sulfonyl chlorideHCID 672239156-benzylamino-3,4-dihydro-2H-isoquinolin-1-one

Product 1

HCID 672239981-methyl-1H-pyrazole-3-sulfonic acid benzyl-(1-oxo-1,2,3,4-tetrahydro-isoquinolin-6-yl)-amide

Sources & evidence

ORD record
ord-9a7d097c1bb04d578862847647aea7ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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