Ethyl [2-(benzyloxy)ethoxy]acetate → Ethyl (2-hydroxyethoxy)acetate
Reaction equation
C([O:8][CH2:9][CH2:10][O:11][CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14])C1C=CC=CC=1>[C].[Pd].CO>[OH:8][CH2:9][CH2:10][O:11][CH2:12][C:13]([O:15][CH2:16][CH3:17])=[O:14]Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
A mixture of ethyl (2-benzyloxyethoxy)acetate (0.50 g, 1.88 mmol), 10% palladium-carbon (0.05 g) and methanol (10 ml) was stirred under a hydrogen atmosphere at room temperature for 5 hours. The catalyst was filtered off and the filtrate was concentrated under reduced pressure to obtain 0.29 g of ethyl (2-hydroxyethoxy)acetate as a colorless oil.
Workup
- filtrationThe catalyst was filtered off
- concentrationthe filtrate was concentrated under reduced pressure
Sources & evidence
- ORD record
- ord-c1478e9d37654a0c811079246e58ac70
- Source dataset
- uspto-grants-1999_11
- Patent number
- US05977100
Reaction notes
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