1,1-Bis(benzyloxy)trimethylamine → HCID 178484261, compound

HRID 1602254Notes

Reaction equation

HRID 1602254 reaction equation
[NH2:1][C:2]1[NH:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([N+:13]([O-:15])=[O:14])[CH:8]=2)[C:3]=1[C:16]#[N:17].C(O[CH:26](OCC1C=CC=CC=1)[N:27]([CH3:29])[CH3:28])C1C=CC=CC=1>C1(C)C=CC=CC=1>[N+:13]([C:9]1[CH:8]=[C:7]([C:4]2[C:3]([C:16]#[N:17])=[C:2]([N:1]=[CH:26][N:27]([CH3:29])[CH3:28])[NH:6][N:5]=2)[CH:12]=[CH:11][CH:10]=1)([O-:15])=[O:14]

Participants

4

Reactant 2

HCID 748371,1-Bis(benzyloxy)trimethylamineHCID 178509380HCID 178509380, compound

Product 1

HCID 178484261HCID 178484261, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In 8 ml of toluene, 229 mg (1.00 mmol) of 5-amino-3-(3-nitro-phenyl)-1H-pyrazole-4-carbonitrile and 317 μl of N,N-dimethylformamide dibenzylacetal are boiled overnight. Cooling, filtering the suspension and washing with hexane yield N'-[3-(3-nitrophenyl)-4-cyano-1H-pyrazol-5-yl]-N,N-dimethylformamidine; m.p. 221-225° C.; TRet (Grad22-100)=8.7.

Workup

  1. temperatureCooling
  2. filtrationfiltering the suspension
  3. washwashing with hexane

Sources & evidence

ORD record
ord-c2bf4497cd944fc8b4584857be76c2bb
Source dataset
uspto-grants-1999_11
Patent number
US05981533

Reaction notes

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