2-Chloro-4-methylpyrimidine → N-[2-chloro-3-[2-(2-chloropyrimidin-4-yl)-1-hydroxyethenyl]phenyl]-2,6-difluorobenzenesulfonamide

HRID 160419

Reaction equation

HRID 160419 reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH:8]=[C:9]([OH:10])[c:11]2[cH:12][c:13]([NH:17][S:18](=[O:19])(=[O:20])[c:21]3[c:22]([F:28])[cH:23][cH:24][cH:25][c:26]3[F:27])[cH:14][cH:15][cH:16]2)[n:7]1.[Cl:29][c:30]1[c:31]([NH:32][S:33]([c:34]2[c:35]([F:36])[cH:37][cH:38][cH:39][c:40]2[F:41])(=[O:42])=[O:43])[cH:44][cH:45][cH:46][c:47]1[C:48]([O:49][CH3:50])=[O:51].[Cl:52][c:53]1[n:54][c:55]([CH3:56])[cH:57][cH:58][n:59]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([CH:8]=[C:9]([OH:10])[c:11]2[c:12]([Cl:29])[c:13]([NH:17][S:18](=[O:19])(=[O:20])[c:21]3[c:22]([F:28])[cH:23][cH:24][cH:25][c:26]3[F:27])[cH:14][cH:15][cH:16]2)[n:7]1

Participants

4

Reactant 3

HCID 116296072-Chloro-4-methylpyrimidineHCID 57989637Methyl 2-chloro-3-(2,6-difluorophenylsulfonamido)benzoateHCID 154041434N-[3-[2-(2-chloropyrimidin-4-yl)-1-hydroxyethenyl]phenyl]-2,6-difluorobenzenesulfonamide

Product 1

HCID 154041436N-[2-chloro-3-[2-(2-chloropyrimidin-4-yl)-1-hydroxyethenyl]phenyl]-2,6-difluorobenzenesulfonamide

Sources & evidence

ORD record
ord-b16113bda5d24d44bc309afe4f0a7b39
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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