Peracetic Acid → 2-Methoxy-5-methylphenol

HRID 1605632Notes

Reaction equation

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][CH:3]=1.C(OO)(=[O:12])C>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[C:4]([OH:12])[CH:3]=1

Participants

Reactant 2

HCID 6585Peracetic Acid

HCID 77314-Methylanisole2×

Product 1

HCID 145192-Methoxy-5-methylphenol

Procedure

The procedure of Example 18 was repeated, except Victor Wet 35B (phosphur-containing ester) was used as a reaction catalyst and 4-methyl anisole was used in place of anisole. Consequently, the conversion of peracetic acid was 96.2%, the conversion of 4-methyl anisole was 8.02% and there was formed 4.55g of 4-methyl-2-hydroxy anisole.

Sources & evidence

ORD record: ord-a21e2ecaa3fe4d47a4d24999fc9804d4
Source dataset: uspto-grants-1976_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03950437

Reaction notes

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