Thionyl Chloride → HCID 12450695, compound

Reaction equation

[OH:1][CH:2]1[C:6]([CH3:7])=[C:5]([CH3:8])[C:4](=O)[O:3]1.S(Cl)([Cl:12])=O>>[Cl:12][CH:4]1[C:5]([CH3:8])=[C:6]([CH3:7])[C:2](=[O:1])[O:3]1

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 27528902(5H)-Furanone, 5-hydroxy-3,4-dimethyl-

Product 1

HCID 12450695HCID 12450695, compound

Procedure

A mixture of 6.6g of 2-hydroxy-3,4-dimethyl-5-oxo-2,5-dihydrofuran and 10 ml of thionyl chloride was stirred for 2 hours at room temperature. By concentrating the reaction mixture under reduced pressure, 7.5g of light-yellowish oily 2-chloro-3,4-dimethyl-5-oxo-2,5-dihydrofuran was obtained.

Workup

concentrationBy concentrating the reaction mixture under reduced pressure

Sources & evidence

ORD record: ord-50fe49a96bdc4898b4393489f015e892
Source dataset: uspto-grants-1976_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03951954

Reaction notes

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