Dipropylcarbamoyl chloride → 1-Dipropylcarbamoyl-3-isopropylsulphonyl-1,2,4-triazole
Reaction equation
[CH:1]([S:4]([C:7]1[N:11]=[CH:10][NH:9][N:8]=1)(=[O:6])=[O:5])([CH3:3])[CH3:2].[CH2:12]([N:15]([CH2:19][CH2:20][CH3:21])[C:16](Cl)=[O:17])[CH2:13][CH3:14]>>[CH2:12]([N:15]([CH2:19][CH2:20][CH3:21])[C:16]([N:9]1[CH:10]=[N:11][C:7]([S:4]([CH:1]([CH3:3])[CH3:2])(=[O:6])=[O:5])=[N:8]1)=[O:17])[CH2:13][CH3:14]Participants
3
Procedure
In an analogous manner to that described in Example 20, 3-isopropylsulphonyl-1,2,4-triazole was reacted with dipropylcarbamoyl chloride (4 hours reflux) to give 1-dipropylcarbamoyl-3-isopropylsulphonyl-1,2,4-triazole, m.p. 61° .varies. 63°C. Elemental analysis satisfactory.
Sources & evidence
- ORD record
- ord-36aa681447654db7a369731598887872
- Source dataset
- uspto-grants-1976_04
- Patent number
- US03952001