1-Cyano-2-ethoxy-2-methylaminoethylene → HCID 178483853, compound

HRID 1606545

Reaction equation

HRID 1606545 reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][NH:5][C:6]=1[CH2:7][S:8][CH2:9][CH2:10][NH2:11].[C:12]([CH:14]=[C:15](OCC)[NH:16][CH3:17])#[N:13]>>[C:12]([CH:14]=[C:15]([NH:16][CH3:17])[NH:11][CH2:10][CH2:9][S:8][CH2:7][C:6]1[NH:5][CH:4]=[N:3][C:2]=1[CH3:1])#[N:13]

Participants

3

Reactant 2

HCID 736832021-Cyano-2-ethoxy-2-methylaminoethyleneHCID 178433288HCID 178433288, compound

Product 1

HCID 178483853HCID 178483853, compound

Procedure

4-Methyl-5-[(2-aminoethyl)thiomethyl]imidazole (3.5g) was added to a solution of 1-cyano-2-ethoxy-2-methylaminoethylene (3.1g) and the solution was stirred for 5 hours at 100°. The product was chromatographed on a column of neutral alumina with elution bychloroform/ethyl acetate (1:1) to give the title compound as a glass.

Workup

  1. customThe product was chromatographed on a column of neutral alumina with elution bychloroform/ethyl acetate (1:1)

Sources & evidence

ORD record
ord-dde605242e8b4fdc815d58849b162fa5
Source dataset
uspto-grants-1976_04
Patent number
US03953460

Linked notes

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