Ethanol → Butyric acid (4-quinolinylmethylene)hydrazide

HRID 1608175

Reaction equation

HRID 1608175 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]=O)=[CH:3][CH:2]=1.[C:13]([NH:18][NH2:19])(=[O:17])[CH2:14][CH2:15][CH3:16].C(O)C>O>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]=[N:19][NH:18][C:13](=[O:17])[CH2:14][CH2:15][CH3:16])=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 77079ButyrohydrazideHCID 780724-Quinolinecarboxaldehyde

Product 1

HCID 86743403Butyric acid (4-quinolinylmethylene)hydrazideYield 85.4%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 7.85 gm (0.05 mole) of 4-quinolinecarboxaldehyde, 5.11 gm (0.05 mole) of butyric acid hydrazide and 100 ml of ethanol is refluxed 4 hr. The reaction mixture is diluted with water and cooled to room temperature. The mixture is chilled. The solid that separates is collected, washed with water and dried to give 10.3 gm of the title compound, having a melting point of 130.4° C.

Workup

  1. temperatureis refluxed 4 hr
  2. temperatureThe mixture is chilled
  3. customThe solid that separates is collected
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-86b41a2e023d46cfa519dc8f0d867f61
Source dataset
uspto-grants-1989_09
Patent number
US04870082

Linked notes

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