Allyl Alcohol → (3-Allyl-)heptafluorobutan-2-one

HRID 1609146

Reaction equation

HRID 1609146 reaction equation
[F:1][C:2]([F:12])([F:11])[C:3]([F:10])=[C:4](F)[C:5]([F:8])([F:7])[F:6].[CH2:13](O)[CH:14]=[CH2:15].[OH-:17].[K+]>O>[CH2:15]([C:3]([F:10])([C:2]([F:1])([F:11])[F:12])[C:4](=[O:17])[C:5]([F:6])([F:7])[F:8])[CH:14]=[CH2:13]

Participants

5

Reactant 3

HCID 7858Allyl AlcoholHCID 96781,1,1,2,3,4,4,4-Octafluorobut-2-eneHCID 14797Potassium Hydroxide

Product 1

HCID 22074693(3-Allyl-)heptafluorobutan-2-one

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

396 g (1.98 mol) of octafluorobut-2-ene is condensed into 116 g (2 mol) of allyl alcohol at -5° C. Then 113 g (1.98 mol) of KOH, dissolved in 150 ml of water, is slowly added dropwise over the course of 3 hours, the temperature being maintained at 0°-5° C. Stirring continues overnight at room temperature and working-up is performed in the same way as in Example 2a.

Workup

  1. additionis slowly added dropwise over the course of 3 hours
  2. temperaturethe temperature being maintained at 0°-5° C

Sources & evidence

ORD record
ord-5344c9fec59d4d58975ffa741fb2bfb6
Source dataset
uspto-grants-1995_03
Patent number
US05399645

Linked notes

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