Methanol → 2-(Aminomethyl)benzofuran

Reaction equation

[CH3:14][OH:15].[N:1](=[N+:2]=[N-:3])[CH2:4][c:5]1[o:6][c:7]2[c:8]([cH:9]1)[cH:10][cH:11][cH:12][cH:13]2.[OH-:16].[OH-:17].[Pd+2:18]>>[NH2:1][CH2:4][c:5]1[o:6][c:7]2[c:8]([cH:9]1)[cH:10][cH:11][cH:12][cH:13]2

Participants

Reactant 4

HCID 887Methanol

HCID 961Hydroxide2×

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 866474332-(Azidomethyl)benzofuran

Product 1

HCID 190793482-(Aminomethyl)benzofuran

Sources & evidence

ORD record: ord-3b8cc212a6a24fdfadf605934ab5846c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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